Study Design details for SD# 9
Reference Details
| Title | Authors | Year | DOI |
|---|---|---|---|
| Effects of polystyrene micro/nanoplastics on liver cells based on particle size, surface functionalization, concentration and exposure period | Amrita Banerjee, Lloyd O. Billey, Amy M. McGarvey, Weilin L. Shelver | 2022 | https://doi.org/10.1016/j.scitotenv.2022.155621 |
Study Type: in vitro
Regimen description
Hepatocyte cells were used to assess cellular uptake, cell viability, apoptosis, and inflammatory responses when exposed to various concentrations, sizes, and functionalities of nano and microplastics. The inflammatory response of the cells was determined by first exposing them to concentrations of the nano and microplastics and then measuring the concentrations of various pro-inflammatory cytokines, which can be indicative of a decrease in cell viability.
Subject Properties
| Taxon Term | Strain | Sex | Life Stage |
|---|---|---|---|
| human | Unspecific |
Observations
| ID | Stressor | Sample (short_name) | Assay | Effect | Associated Key Events | |
|---|---|---|---|---|---|---|
| 9 | 16: 4-24 hours , hepatocyte | Inflammatory cellular response | increased |
|