Study Design details for SD# 4

Reference Details
Title Authors Year DOI
ARE-Nrf2 Luciferase Test Method for Keratinocyte activation OECD
Study Type: in vitro
Regimen description

This is an example how regiment? or study design  (protocol) does not need to be stressor specific. However, in the TG the whole study design/protocol contains not just the experimental protocol but also the prediction model which relates to the AO, not to the KE (i.e. Luc expression as proxy for Nrf2).

Assays measure KEs and studies sometimes measure association/correlation of 2 KEs (i.e. KER) to evaluate likelihood of causality.

Subject Properties
Taxon Term Strain Sex Life Stage
human and other cells in culture maybe have a line for the specific cell type and another for its origin. How difficult would it be to enable user to add lines, like in xcel?

Observations

ID Stressor Sample (short_name) Assay Effect Associated Key Events
4 ARE-Nrf2 Luciferase Test Method for evaluation of Keratinocyte activation increased