{"id":95,"title":"Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival","short_name":"ether-a-go-go (ERG) inhibition","created_at":"2016-11-29T18:41:16.000-05:00","updated_at":"2023-09-25T16:26:49.000-04:00","corresponding_author":{"id":17712,"created_at":"2023-09-11T18:10:58.000-04:00","updated_at":"2023-09-11T18:10:58.000-04:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":593,"event":"Inhibition, Ether-a-go-go (ERG) voltage-gated potassium channel ","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":585,"event":"Decreased, Sodium conductance 1","event_type":"KeyEvent"},{"event_id":586,"event":"Reduced, swimming speed","event_type":"KeyEvent"},{"event_id":587,"event":"Reduced, feeding 1","event_type":"KeyEvent"},{"event_id":588,"event":"Increased, predation","event_type":"KeyEvent"}],"aop_aos":[{"event_id":592,"event":"Reduced, survival","event_type":"AdverseOutcome"}],"relationships":[{"relation":292,"upstream_event_id":585,"upstream_event":"Decreased, Sodium conductance 1","downstream_event_id":586,"downstream_event":"Reduced, swimming speed"},{"relation":293,"upstream_event_id":586,"upstream_event":"Reduced, swimming speed","downstream_event_id":587,"downstream_event":"Reduced, feeding 1"},{"relation":294,"upstream_event_id":586,"upstream_event":"Reduced, swimming speed","downstream_event_id":588,"downstream_event":"Increased, predation"},{"relation":295,"upstream_event_id":587,"upstream_event":"Reduced, feeding 1","downstream_event_id":588,"downstream_event":"Increased, predation"},{"relation":296,"upstream_event_id":588,"upstream_event":"Increased, predation","downstream_event_id":592,"downstream_event":"Reduced, survival"},{"relation":297,"upstream_event_id":593,"upstream_event":"Inhibition, Ether-a-go-go (ERG) voltage-gated potassium channel ","downstream_event_id":585,"downstream_event":"Decreased, Sodium conductance 1"}]}