PR:000007204
PR
estrogen receptor
D014819
MESH
vitellogenins
UBERON:0005777
UBERON
glomerular basement membrane
GO:0030284
GO
estrogen receptor activity
GO:0010467
GO
gene expression
MP:0001914
MP
hemorrhage
HP:0000112
HP
Nephropathy
1
WIKI
increased
7
WIKI
functional change
Agonism, Estrogen receptor
Agonism, Estrogen receptor
Molecular
CL:0000182
CL
hepatocyte
AOPWiki
2016-11-29T18:41:22
2017-09-16T10:14:44
Increased, Vitellogenin synthesis
Increased, Vitellogenin synthesis
Cellular
CL:1000497
CL
kidney cell
AOPWiki
2016-11-29T18:41:24
2017-09-16T10:15:09
Increase, Plasma vitellogenin concentrations
Increase, Plasma vitellogenin concentrations
Organ
UBERON:0001969
UBERON
blood plasma
AOPWiki
2016-11-29T18:41:23
2017-09-16T10:14:44
Increased, renal vitellogenin deposition
Increased, renal vitellogenin deposition
Organ
UBERON:0002113
UBERON
kidney
AOPWiki
2016-11-29T18:41:24
2017-09-16T10:15:10
Increased, glomerular rupture and renal hemorrhaging
Increased, glomerular rupture and renal hemorrhaging
Organ
UBERON:0002113
UBERON
kidney
AOPWiki
2016-11-29T18:41:24
2017-09-16T10:15:10
Increased, nephropathy
Increased, nephropathy
Individual
AOPWiki
2016-11-29T18:41:24
2016-12-03T16:37:50
ER agonism leading to reduced survival due to renal failure
ER agonism : reduced survival
Brendan Ferreri-Hanberry
BY-SA
1.29
1.0
AOPWiki
2016-11-29T18:41:16
2023-09-25T16:26:47