{"id":498,"title":"Increased LCN2/iron complex leading to neurological disorders","short_name":"Lipocalin 2/Iron complex increases, Cognative dysfunction","created_at":"2023-06-12T05:11:18.000-04:00","updated_at":"2023-09-25T16:27:14.000-04:00","corresponding_author":{"id":17717,"created_at":"2023-09-11T18:10:59.000-04:00","updated_at":"2023-09-12T12:20:02.000-04:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":2148,"event":"Increased LCN2/iron complex  binds to SLC22A17 receptor in neuron ","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":2149,"event":"Increased intracelluar Iron accumulation","event_type":"KeyEvent"},{"event_id":191,"event":"Neuronal dysfunction","event_type":"KeyEvent"}],"aop_aos":[{"event_id":2150,"event":"Neurological disorder","event_type":"AdverseOutcome"}],"relationships":[{"relation":3489,"upstream_event_id":2148,"upstream_event":"Increased LCN2/iron complex  binds to SLC22A17 receptor in neuron ","downstream_event_id":2149,"downstream_event":"Increased intracelluar Iron accumulation"},{"relation":3490,"upstream_event_id":2149,"upstream_event":"Increased intracelluar Iron accumulation","downstream_event_id":191,"downstream_event":"Neuronal dysfunction"},{"relation":3491,"upstream_event_id":191,"upstream_event":"Neuronal dysfunction","downstream_event_id":2150,"downstream_event":"Neurological disorder"}]}