{"id":479,"title":"Mitochondrial complexes inhibition leading to heart failure via increased myocardial oxidative stress","short_name":"Mitochondrial complexes inhibition leading to heart failure","created_at":"2023-01-05T04:27:28.000-05:00","updated_at":"2023-09-25T16:27:13.000-04:00","corresponding_author":{"id":17716,"created_at":"2023-09-11T18:10:59.000-04:00","updated_at":"2023-11-28T16:27:24.000-05:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":105,"event":"Inhibition, Mitochondrial Electron Transport Chain Complexes","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":177,"event":"N/A, Mitochondrial dysfunction 1","event_type":"KeyEvent"},{"event_id":1392,"event":"Oxidative Stress ","event_type":"KeyEvent"},{"event_id":55,"event":"Cell injury/death","event_type":"KeyEvent"},{"event_id":2084,"event":"Increase, Cardiac remodelling","event_type":"KeyEvent"},{"event_id":1532,"event":"Decrease, Cardiac contractility ","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1535,"event":"Heart failure ","event_type":"AdverseOutcome"},{"event_id":350,"event":"Increase, Mortality","event_type":"AdverseOutcome"}],"relationships":[]}