{"id":400,"title":"Increased (ectopic) concentration of all-trans retinoic acid (ATRA) if fetal testis leading to reduced sperm count, males","short_name":"Ectopic ATRA in fetal testis leads to reduced spem count","created_at":"2021-05-29T12:26:47.000-04:00","updated_at":"2023-09-25T16:27:07.000-04:00","corresponding_author":{"id":17713,"created_at":"2023-09-11T18:10:58.000-04:00","updated_at":"2023-12-20T10:05:07.000-05:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":1888,"event":"Increased (ectopic) all-trans retinoic acid concentration","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1889,"event":"Premature initiation of meiosis in fetal male germ cells","event_type":"KeyEvent"},{"event_id":1890,"event":"Decrease (loss of) fetal male germ cells","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1757,"event":"Reduce, Sperm count","event_type":"AdverseOutcome"}],"relationships":[{"relation":2892,"upstream_event_id":1888,"upstream_event":"Increased (ectopic) all-trans retinoic acid concentration","downstream_event_id":1889,"downstream_event":"Premature initiation of meiosis in fetal male germ cells"}]}