{"id":286,"title":"Mitochondrial complex III antagonism leading to growth inhibition (1)","short_name":"Mitochondrial complex III antagonism leading to growth inhibition (1)","created_at":"2019-03-19T08:35:17.000-04:00","updated_at":"2023-09-25T16:26:59.000-04:00","corresponding_author":{"id":17716,"created_at":"2023-09-11T18:10:59.000-04:00","updated_at":"2023-11-28T16:27:24.000-05:00","subscribed":true,"novice":null},"aop_stressors":[{"stressor_id":395,"stressor_name":"Antimycin A"}],"aop_mies":[{"event_id":1542,"event":"Increase, Mitochondrial complex III antagonism","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1771,"event":"Decrease, Adenosine triphosphate pool","event_type":"KeyEvent"},{"event_id":1821,"event":"Decrease, Cell proliferation","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1521,"event":"Decrease, Growth","event_type":"AdverseOutcome"}],"relationships":[{"relation":2421,"upstream_event_id":1542,"upstream_event":"Increase, Mitochondrial complex III antagonism","downstream_event_id":1771,"downstream_event":"Decrease, Adenosine triphosphate pool"},{"relation":2422,"upstream_event_id":1771,"upstream_event":"Decrease, Adenosine triphosphate pool","downstream_event_id":1821,"downstream_event":"Decrease, Cell proliferation"},{"relation":2423,"upstream_event_id":1821,"upstream_event":"Decrease, Cell proliferation","downstream_event_id":1521,"downstream_event":"Decrease, Growth"}]}