{"id":279,"title":"Microtubule interacting drugs lead to peripheral neuropathy","short_name":"Microtubule interacting drugs lead to peripheral neuropathy","created_at":"2019-01-29T08:39:38.000-05:00","updated_at":"2023-09-25T16:26:59.000-04:00","corresponding_author":{"id":17713,"created_at":"2023-09-11T18:10:58.000-04:00","updated_at":"2023-12-20T10:05:07.000-05:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":1580,"event":"Binding of microtubule stabilizing agents (MSA) to microtubules","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1581,"event":"Disturbance in microtubule dynamic instability","event_type":"KeyEvent"},{"event_id":1582,"event":"Impaired axonial transport","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1583,"event":"Sensory axonal peripheral neuropathy","event_type":"AdverseOutcome"}],"relationships":[{"relation":1769,"upstream_event_id":1580,"upstream_event":"Binding of microtubule stabilizing agents (MSA) to microtubules","downstream_event_id":1581,"downstream_event":"Disturbance in microtubule dynamic instability"},{"relation":1770,"upstream_event_id":1581,"upstream_event":"Disturbance in microtubule dynamic instability","downstream_event_id":1582,"downstream_event":"Impaired axonial transport"},{"relation":1771,"upstream_event_id":1582,"upstream_event":"Impaired axonial transport","downstream_event_id":1583,"downstream_event":"Sensory axonal peripheral neuropathy"}]}