{"id":268,"title":"Uncoupling of oxidative phosphorylation leading to growth inhibition via mitochondrial swelling","short_name":"Uncoupling of OXPHOS leading to growth inhibition 6","created_at":"2018-06-12T04:33:44.000-04:00","updated_at":"2023-09-25T16:26:58.000-04:00","corresponding_author":{"id":17716,"created_at":"2023-09-11T18:10:59.000-04:00","updated_at":"2023-11-28T16:27:24.000-05:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":1446,"event":"Decrease, Coupling of oxidative phosphorylation","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":2072,"event":"Increase, Mitochondrial swelling","event_type":"KeyEvent"},{"event_id":55,"event":"Cell injury/death","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1521,"event":"Decrease, Growth","event_type":"AdverseOutcome"}],"relationships":[{"relation":3270,"upstream_event_id":1446,"upstream_event":"Decrease, Coupling of oxidative phosphorylation","downstream_event_id":2072,"downstream_event":"Increase, Mitochondrial swelling"},{"relation":3271,"upstream_event_id":2072,"upstream_event":"Increase, Mitochondrial swelling","downstream_event_id":55,"downstream_event":"Cell injury/death"},{"relation":3272,"upstream_event_id":55,"upstream_event":"Cell injury/death","downstream_event_id":1521,"downstream_event":"Decrease, Growth"}]}