{"id":115,"title":"Epithelial cytotoxicity leading to forestomach tumors (in mouse and rat)","short_name":"Epithelial cytotoxicity- forestomach tumor","created_at":"2016-11-29T18:41:16.000-05:00","updated_at":"2023-09-25T16:26:50.000-04:00","corresponding_author":{"id":17716,"created_at":"2023-09-11T18:10:59.000-04:00","updated_at":"2023-11-28T16:27:24.000-05:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":780,"event":"Increase, Cytotoxicity (epithelial cells)","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":149,"event":"Increase, Inflammation","event_type":"KeyEvent"},{"event_id":781,"event":"Increase, Regenerative cell proliferation (forestomach epithelial cells)","event_type":"KeyEvent"},{"event_id":782,"event":"Increase, Hyperplasia (forestomach epithelial cells)","event_type":"KeyEvent"}],"aop_aos":[{"event_id":779,"event":"Increase, Papillomas/carcinomas (squamous cells)","event_type":"AdverseOutcome"}],"relationships":[{"relation":441,"upstream_event_id":780,"upstream_event":"Increase, Cytotoxicity (epithelial cells)","downstream_event_id":149,"downstream_event":"Increase, Inflammation"},{"relation":442,"upstream_event_id":149,"upstream_event":"Increase, Inflammation","downstream_event_id":781,"downstream_event":"Increase, Regenerative cell proliferation (forestomach epithelial cells)"},{"relation":443,"upstream_event_id":781,"upstream_event":"Increase, Regenerative cell proliferation (forestomach epithelial cells)","downstream_event_id":782,"downstream_event":"Increase, Hyperplasia (forestomach epithelial cells)"},{"relation":444,"upstream_event_id":782,"upstream_event":"Increase, Hyperplasia (forestomach epithelial cells)","downstream_event_id":779,"downstream_event":"Increase, Papillomas/carcinomas (squamous cells)"}]}